Non-invasive parental testing is advanced technology that reveals fetal chromosomal aneuploidy by screening fetus’s cell free DNA present in the bloodstream of the pregnant woman. This has dramatically shortened the chances of fetus being born with genetic defects or chromosomal abnormalities.Non-invasive parental testing can be performed at 10th week or later as cell free fetal DNA increases over time. NIPT serves as intermediate test between serum screening and invasive diagnostic techniques. As compared to serum screening NIPT is more accurate and efficient as it produces fewer false results. NIPT along with chromosomal deformities detects RH blood type and gender. Although circulating cffDNA, RNA and intact fetal cells can all be used to analyse genetic status of the fetus non-invasively, cfffDNA is more stable, abundant and remains in maternal circulation for only few days after each pregnancy, makes it more suitable for pregnancy specific testing.
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Market Growth Factors
Rapid increase in genetic disorders & chromosomal abnormalities has shifted the need towards early detection of these diseases driving the market growth. Furthermore, advantages offered by NIPT such as non-invasiveness, high precision, rising awareness among people and continuous increase in maternal average age are some another factor acting in favour of the non-invasive parental testing market. However, the market is facing regulatory and ethical obstacles related to implementation of NIPT believing that it is likely to raise the incidence of miscarriages. Unmet stringent usage regulatory guideline provided by various organizations and high cost for overall treatment might post restrain hampering the market growth in coming future.
The non-invasive parental testing market is segmented on the basis of product, method, application, end-user and region. By product type it is divided into consumables and instruments. Based on method the market is bifurcated into biochemical screening test, ultrasonic detection, cell free DNA in maternal plasma test and fetal cells in maternal blood test. Ultrasonic detection followed by cell free DNA in maternal plasma test segment is anticipated to grow at faster rate owing initiatives taken by government to provide best of parental service. On the basis of application market is categorized into micro-deletion syndrome, trisomy and other application. Trisomy is expected to witness the growth. Factors attributing to growth of this segment are increased average age for maternity and high prevalence of chromosomal abnormalities. Considering end user the market is differentiated into hospitals, diagnostic laboratories and others.
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Based on geography the global non-invasive parental testing market is studied across North America, Europe, Asia-Pacific and Rest of the word. North America accounts for significant value share of the market primarily owing to fluctuating maternal age, genetic disorders and rising healthcare infrastructure along with awareness programmes. Asia-Pacific is expected to record significant growth. The growth of this market will attributed to increasing disposable income, conduction of awareness programme and conferences and market penetration by new players.
The non-invasive parental testing market is characterized by the presence of numerous global and regional players. Some dominant players in the market are GE Healthcare, F. Hoffmann-La Roche Ltd., QIAGEN N.V., Illumina, Natera, Inc., Agilent Technologies, Inc., Thermo Fisher Scientific, Inc., and BGI Diagnostics.
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